Introducing SMILE – Cutting-Edge Technology Meets Natural Minerals

Gum recession and periodontal disease affect millions, leading to tooth sensitivity, decay, and even tooth loss. A new generation of toothpaste combines cutting-edge science with natural minerals to actively repair gum tissue and restore oral health. The formula works synergistically to reverse gum loss, whiten, and remineralize teeth.

The Power of Peptides: BPC-157 and GHK-Cu

BPC-157, a peptide originally derived from stomach proteins, accelerates tissue repair by stimulating collagen production and reducing inflammation. It regenerates receding gums by activating genes that promote blood vessel growth and nerve repair. (1)

GHK-Cu, a copper peptide, enhances wound healing by boosting collagen synthesis and reducing oxidative stress. Studies show GHK-Cu increases anti-inflammatory cytokines while decreasing pro-inflammatory ones, creating an optimal environment for gum regeneration. (2)

Together, these peptides don’t just manage symptoms—they rebuild damaged gum structures at the cellular level.

Protect, Remineralize and Whiten

Mineral Marvels: Hydroxyapatite and Calcium Carbonate

Hydroxyapatite, the primary mineral in tooth enamel, remineralizes teeth and forms a protective barrier over gums. (3) Specially formulated nanoparticles in this advanced technology toothpaste work to do just that: remineralize and protect delicate tooth enamel.

Calcium carbonate complements this by neutralizing acidic plaque and strengthening gum tissue through collagen support. (4) Unlike abrasive whitening agents, these minerals restore enamel and gums without irritation.

Gentle Whitening and Defense

Traditional whitening agents like hydrogen peroxide weaken enamel and inflame gums. PAP+ (phthalimidoperoxycaproic acid) offers stain removal without sensitivity by combining with hydroxyapatite to protect enamel during oxidation. (5)

Zinc lactate tackles harmful bacteria, reducing plaque buildup and halitosis while calming gum inflammation. (6) This dual action keeps gums healthy while maintaining a bright smile.

Why Older Toothpastes Can’t Compete

Other brands rely on stannous fluoride or zinc citrate to reduce bleeding and plaque. While effective for symptom management, many of them lack:

1. Tissue-regenerating peptides (BPC-157/GHK-Cu)
2. Enamel-rebuilding hydroxyapatite
3. Sensitivity-free whitening (PAP+ vs. tissue-damaging peroxide)

The Future of Oral Care

This advanced formula represents a paradigm shift—from damage control to active repair. By combining peptide-driven regeneration with mineral reinforcement and gentle whitening, it addresses gum loss at its root cause, rendering traditional “anti-gingivitis” toothpastes obsolete.

References

1. Keremi B, et al. (2009). Antiinflammatory effect of BPC 157 on experimental periodontitis in rats. J Physiol Pharmacol, 60 Suppl 7:115–22. PMID: 20388954.
2. Pickart L, Margolina A. (2018). Regenerative and Protective Actions of the GHK-Cu Peptide. Int J Mol Sci, 19(7):1987. doi:10.3390/ijms19071987.
3. O'Hagan-Wong K, et al. (2022). The use of hydroxyapatite toothpaste to prevent dental caries. Odontology, 110(2):223–230. doi:10.1007/s10266-021-00675-4.
4. Vorst Canada. (2023). Calcium Carbonate Mechanisms.
5. Pascolutti M, de Oliveira D. (2021). A Radical-Free Approach to Teeth Whitening. Dent J (Basel), 9(12):148. doi:10.3390/dj9120148.
6. Zinc lactate in oral care. (2019). Journal of Clinical Dentistry, 30(1), 1–6.