Introducing APPETITE – curb your appetite naturally

A revolutionary probiotic formula that activates both GLP-1 and GLP-2 while healing and restoring intestinal health is now available. APPETITE, a proprietary blend of probiotic and prebiotics, can help you:

• Manage weight
• Feel fuller
• Boost metabolism

What are GLP-1 and GLP-2 hormones?

You may have heard of the GLP-1 hormone in weight loss and diabetic medication use; however, little attention is given to the GLP-2 hormone.

GLP-1 and GLP-2 are hormones that help regulate blood sugar, appetite, and digestion.

GLP-1 plays a key role in controlling blood sugar, while GLP-2 focuses on maintaining a healthy gut by promoting nutrient absorption and blood flow. ⁽¹⁾

GLP-1: The Blood Sugar and Appetite Regulator

• GLP-1 helps your body manage blood sugar after eating.
• Plays a part in balancing insulin and glucagon to regulate blood sugar.
• Slows down how fast your stomach empties, making you feel full longer and helping with weight control.
• Because of these effects, medicines that mimic GLP-1 are used to treat type 2 diabetes and help with weight loss.

GLP-2: The Gut Repair and Growth Hormone ^(1,2)

• GLP-2 helps keep your intestines healthy and working well.
• Promotes growth and repair of the lining of your intestines, helping them absorb nutrients better and heal from injury.
• Used in treatments for people with gut problems, like short bowel syndrome.
• GLP-2 may also help protect bones by increasing bone mass.

APPETITE is a research-backed formula that complements each ingredient, unlocking its true potential to reduce appetite, balance blood sugar, increase metabolism, promote a healthy gut environment, reduce inflammation, and more:

Ingredients:

Akkermansia: The Gut Barrier Guardian ^(3,4,5)

• Colonizes the intestinal mucus layer, enhancing gut integrity and metabolic health.
• Stimulates glucagon-like peptide-1 (GLP-1) secretion.
• Improves insulin sensitivity.
• Reduces inflammation in type 2 diabetes.

C. butyricum and B. infantis: ^(6,7,8)

• Enhance GLP-1 and GLP-2, leading to appetite control and a healthy intestinal microbiome.
• Break down fiber from your food and produce butyrate, which fuels intestinal cells to release GLP-1 and GLP-2.
• Help balance your gut bacteria by increasing beneficial bacteria and reducing harmful ones.
• Nourish the gut with butyrate and remove harmful bacteria, supporting hormone production.

Inulin and Green Banana: Prebiotic Powerhouses ^(9,10,11)

• Inulin selectively feeds Bacteroidetes, increasing butyrate production and reducing inflammation.
• Green banana flour restores bacterial strains lost during antibiotic use and repairs gut permeability and mucus layer integrity.

Saffron’s Crocetin: A Dual Agonist for Metabolic Health

• Crocetin stimulates GLP-1 and insulin secretion, acting as a potent antidiabetic agent.
• Preclinical studies show its anti-inflammatory benefits, making it a complementary therapy in metabolic syndrome.

Citations

1. Hein GJ, et al. Diabetes. 2013;62(2):373-81. doi: 10.2337/db12-0202
2. Huang YM, et al. Gerontology. 2023;69(4):428-449. doi: 10.1159/000527502
3. Chiantera V, et al. Life (Basel). 2023;13(6):1247. doi: 10.3390/life13061247
4. Si J, et al. Gut Microbes. 2022;14(1):2078619. doi: 10.1080/19490976.2022.2078619
5. Chen T, et al. Front Cell Infect Microbiol. 2021;11:723856. doi: 10.3389/fcimb.2021.723856
6. Chia LW, et al. Beneficial Microbes. 2020;12(1):69–83. doi: 10.3920/BM2020.0005
7. Wang Y, et al. Bioeng Transl Med. 2023;8(3):e10505. doi: 10.1002/btm2.10505
8. Chichlowski M, et al. Nutrients. 2020;12(6):1581. doi: 10.3390/nu12061581
9. Qin YQ, et al. Food Funct. 2023;14(7):2948-2968. doi: 10.1039/d2fo01096h
10. Li P, et al. Front Nutr. 2022;9:832848. doi: 10.3389/fnut.2022.832848
11. Baek GH, et al. Front Nutr. 2023;10:1249358. doi: 10.3389/fnut.2023.1249358
12. Zhao X, et al. Nutrients. 2023;15(22):4774. doi: 10.3390/nu15224774
13. Sani A, et al. Nutrition Metab Insights. 2022;15:11786388221095223. doi: 10.1177/11786388221095223