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Rx

Low Dose Naltrexone

5.0
5.0
Rated 5.0 out of 5 stars
14 Reviews
Rx

Low Dose Naltrexone

5.0
5.0
Rated 5.0 out of 5 stars
14 Reviews
Rx

Low Dose Naltrexone

5.0
5.0
Rated 5.0 out of 5 stars
14 Reviews
$109.99
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$109.99 $109.99
Delivery every 30 days
Subscribe Today! Free U.S. Shipping + No Hidden Fees
$109.99
Delivery every 30 days

Talk to a provider before you buy.

Wondering whether a TWC prescription is right for you? Get your questions answered on a private call, before you spend a dollar on the medication.

Learn More

Target The Root Cause of Chronic Inflammation

Checkmark Reduces inflammation linked to pain and weight gain
Checkmark May reduce inflammation in the brain tied to cognitive decline and fatigue
Checkmark Commonly used to treat conditions like Crohn's, RA, and Fibromyalgia

About Low Dose Naltrexone (LDN)

  • Used to treat autoimmune diseases and viral infections since 1985.
  • Low Dose Naltrexone (LDN) is a prescription medication used in very small doses to help balance an overactive immune system to help reduce chronic inflammation. 
  • It’s different from regular-dose naltrexone. At low doses, it may help the body “re-regulate” systems tied to pain, fatigue, mood, and inflammation. 
  • LDN works by briefly “blocking” certain receptors on immune cells, which can signal the body to make more of its natural endorphins — supporting a healthier immune response and enhanced quality of life over time.
  • Your dose is personalized by a licensed provider, and many people start low and slowly increase based on how they feel. Dosages below 6mg per day are considered low. 


Key Benefits 

  • Improves overactive immune response for improved quality of life
  • Shown to reduce inflammation in the brain which may help reduce fatigue and cognitive decline
  • Targets chronic inflammation to reduce pain, weight gain, and age-related health decline
  • Increases levels of endorphins which may improve energy, mood, and mental clarity 
  • Non-habit forming and designed for long-term use

How To Take

Easy Step-Up Dosing Plan:

  • Month 1: 1 tablet daily (1.5 mg)
  • Month 2: 2 tablets daily (3 mg)
  • Month 3+: 3 tablets daily (4.5 mg)
  • Prescribed by a licensed provider, please take only as directed.
  • LDN is designed for long-term use.

Note:

DO NOT TAKE with opiate pain medications. Additional considerations should be made in persons with thyroid disease or on thyroid medication.

DISCONTINUE use of Low Dose Naltrexone a minimum of 48-hours before or after any surgical procedure or medical diagnostic requiring sedation. Consult with a medical provider for additional information.  

How To Order 

Ordering is as easy as 1-2-3:
Must be 18 years or older to order.

  1. MAKE YOUR PURCHASE
    Click “Add to Cart” and complete checkout. 1Wellness Members save 15%.

  2. COMPLETE YOUR MEDICAL INTAKE
    After checkout, complete a brief medical history form. A licensed provider will review your information to determine eligibility. Some states require a live video visit with a licensed provider before a prescription is issued. We’ll let you know if yours does.

  3. SHIPPING & DELIVERY
    If approved, your prescription is dispensed by a licensed U.S. pharmacy then shipped free, directly to your door. Receive your product in approximately 1-2 weeks once your medical history form and consultation are complete.

For subscriptions, your provider will connect with you every 6 months to check in, answer questions, and adjust care if needed.

Doctor Prescribed

  • Prescribed through our 50-state telemedicine network and dispensed through a licensed U.S. pharmacy.
  • You must be 18 or older to purchase. 

Potential Side Effects

Most people tolerate Low Dose Naltrexone (LDN) well, especially when starting low and increasing slowly.

Still, some users may experience vivid dreams or trouble sleeping (often in the first 1–2 weeks), temporary fatigue or feeling “wired,” headaches, nausea or mild stomach upset, dizziness, anxiety/irritability, or flu-like symptoms as the body adjusts.

Before You Buy

DO NOT TAKE with opiate pain medications. Additional considerations should be made in persons with thyroid disease or on thyroid medication.

DISCONTINUE use of Low Dose Naltrexone a minimum of 48-hours before or after any surgical procedure or medical diagnostic requiring sedation. Consult with a medical provider for additional information.

Support for Complex Chronic Conditions

You likely qualify if you've been told you have 2 or more of the following:

Autoimmune Balance

Autoimmune Balance

LDN is frequently used by those managing autoimmune conditions like Crohn's disease and Rheumatoid Arthritis, where supporting immune function and overall inflammatory balance is important for quality of life.

Fibromyalgia & Chronic Pain

Fibromyalgia & Chronic Pain

LDN is often used by those experiencing fibromyalgia and other chronic pain conditions, where calming underlying inflammation may help support overall comfort and daily function.

Thyroid Health

Thyroid Health

For individuals with autoimmune thyroid conditions such as Hashimoto's, LDN is often used as part of a broader wellness plan to help promote immune regulation and thyroid support.

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Naltrexone

Naltrexone

Helps your body boost natural endorphins that support comfort, mood, and immune function.

Supports healthier inflammation signaling over time (not a quick “band-aid”).

Naltrexone

Naltrexone

Helps your body boost natural endorphins that support comfort, mood, and immune function.

Supports healthier inflammation signaling over time (not a quick “band-aid”).

  • Used to treat autoimmune diseases and viral infections for over 40 years.
  • At low doses, Naltrexone is known for its anti-inflammatory effects and safe for long-term use.
  • Dosages below 6mg per day are considered low. We provide 1.5mg per tablet, with dosing up to 4.5mg per day.
  • Exhibits broad effects across organ systems, mental health, and inflammatory-driven conditions, supporting its longevity-enhancing potential.
  • Ingredients
  • History
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Designed for Real Results

Small Dose, Big Reset 

Support immune balance and reduce chronic inflammation with a single daily dose.

Whole Body Support — Not Just One Symptom

LDN is commonly used in wellness-focused care for immune imbalance, inflammation, pain, fatigue, and brain fog support.

Consistency Matters 

Many people feel benefits after 4–8 weeks, with stronger results over months of steady use. 

Made for Long-Term Wellness

LDN is often used as an ongoing support tool—helping the body stay more balanced over time, not just offering short-term relief.

Small Dose, Big Reset 

Support immune balance and reduce chronic inflammation with a single daily dose.

Whole Body Support — Not Just One Symptom

LDN is commonly used in wellness-focused care for immune imbalance, inflammation, pain, fatigue, and brain fog support.

Consistency Matters 

Many people feel benefits after 4–8 weeks, with stronger results over months of steady use. 

Made for Long-Term Wellness

LDN is often used as an ongoing support tool—helping the body stay more balanced over time, not just offering short-term relief.

Prescription and Delivery Made Simple

Doctor Consults + No Hidden Fees + Free Shipping

1

Fill Out Your Medical Form

1

Fill Out Your Medical Form

Complete a brief medical history form so your provider can review your case.

2

Consult With A Provider

2

Consult With A Provider

Some states require a live video visit with a licensed provider before a prescription is issued. We’ll let you know if yours does.

3

Delivered Free To Your Door

3

Delivered Free To Your Door

Your Rx is dispensed by a licensed U.S. pharmacy and shipped at no extra cost.

Frequently Asked Questions

Do I need a prescription for this product? 

Yes! This medication is prescription-only. But don’t worry – follow the instructions in the link after purchase (also emailed to you) to receive your medical intake form needed to completion your consultation.  
*Based on allergies and other medical details, the medication may not be prescribed without substitution. 

How do I use this product? 

At your consultation, the provider will advise on directions for the use of this product. Take only as directed by your medical provider. 
It is best taken at the same time every day and can be taken with food to avoid stomach irritation.  

What is the tablet size?

Each Low Dose Naltrexone is 8mm wide for ease of swallowing.

Warnings and Side Effects 

Common side effects: 
During the first three to five days of taking LDN, patients may experience mild to moderate levels of the side effects listed. Side effects typically diminish on their own by day five. Common side effects include vivid dreams, fatigue, insomnia, flu-like symptoms, decreased appetite, anxiety, headaches, and dizziness. Patients on thyroid medication may experience heart racing, anxiety, or trouble sleeping.  

CAPSULE TYPE MAY VARY. Hypromellose or bovine gelatin capsules may be used. Notify your doctor of any beef or gelatin allergens.

DO NOT TAKE with opiate pain medications. Additional considerations should be made in persons with thyroid disease or on thyroid medication.
DISCONTINUE use of Low Dose Naltrexone a minimum of 48-hours before any surgical procedure or medical diagnostic requiring sedation. Consult with a medical provider for additional information.  

Are any of the The Wellness Company Rx products covered by insurance

No, The Wellness Company does not accept any type of health insurance or 3rd party payors like Medicare.  

Can I share this product with family members?  

The Wellness Company only offers medications that are prescribed to the specific individual to whom the medication is intended.    
The prescribed medications take into account the individual’s medical status based on the clinical intake form, including any noted allergies. All medications have potential for allergic reactions and other adverse effects. Therefore, it is crucial to not allow others to use medications that were not prescribed for them.    
These medications should be handled with the same caution as any other prescription medication prescribed by a physician. It is important to adhere to the prescribed usage guidelines and avoid sharing the product with family members unless explicitly advised to do so by a healthcare professional. 

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Customer Reviews
5.0
Rated 5.0 out of 5 stars
Based on 14 reviews
100%would recommend this product
Overall SatisfactionRated 5.0 on a scale of 1 to 5
14 reviews
  • Rated 5 out of 5 stars
    6 days ago
    Excellent

    Excellent staff & doctor Was feeling pretty bad then a friend told me to give this a try. Feeling much better. Thank you !!

    CW
    Carey W.
    Verified Buyer
  • Rated 5 out of 5 stars
    1 week ago
    LDN

    This works great. I have severe arthritis in my cervical spine and this helps with the pain. I originally took it because my naturopath recommended it for my recovery from cancer. So the help with pain was actually unexpected.

    PH
    Pamela H.
    Verified Buyer
  • Rated 5 out of 5 stars
    1 week ago
    Low Dose Naltrexone

    I was trying to break 50mg tablets into quarters but that dosage was still problematic for me. I felt super lethargic and would wake up with a headache the morning after taking 12.5mg. I came across the Wellness Company's version of 1.5mg dosing and I thought I'd give it a try. I'm using it in conjunction with The Sinclair Method to cut back on wine consumption. This dose has been perfect for me as all other TWC products that I have tried and use regularly, including Recharge, Longevity, HCl, Ivermectin and PlasDetox. I never leave home without my emergency medical kit and so far have not needed to use it since purchasing. I love this company and will continue to buy and use their products.

    JR
    Jennifer R.
    Verified Buyer
  • Rated 5 out of 5 stars
    1 week ago
    Low does naltrexone

    Excellent results, as advertised. Overall inflammation markers are closer to optimal ranges now.

    TT
    Timothy T.
    Verified Buyer

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