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Published June 2026 · Zenodo

The 1st Real-World Evidence on Pre-Prescribed Emergency Medication Kits

506 verified owners. 333 times they actually reached for the kit. Here is what they reported.

Authored by The Wellness Company's Chief Medical Board & the McCullough Foundation • Self-reported outcomes.

95.8%Net Benefit

Reported an overall net benefit

Across 333 real-world uses of the Medical Emergency Kit

95% CI 93.0–97.5 · self-reported

The problem

Illness doesn't wait for office hours.

Clinics close. Pharmacies sit miles away. A simple infection turns into a long wait and a big bill. The Wellness Company and the McCullough Foundation set out to learn what happens when treatment is already in the house — and ran the first published real-world study of pre-prescribed emergency medication kits.

Care is slow

Weekends, holidays, and appointment delays are exactly when illness strikes.

Care is far

Roughly 1 in 3 users reached for the kit while traveling or in a remote setting.

Care is costly

A single urgent care or ER trip can cost more than the entire kit.

The findings

Real World Results from Medical Kit Users.

Among 333 intended-use episodes: Self-reported outcomes from 506 verified Medical Emergency Kit purchasers. Intended use means the prescribed recipient took the medication.

86.1%

Felt meaningfully better within three days


95% CI 77.1–85.4

95.8%

Reported an overall net benefit


95% CI 93.0–97.5

86.1%

Skipped a clinic, urgent care, or hospital visit


95% CI 82.0–89.4

51.8%

Felt they avoided urgent care or the ER


95% CI 46.4–57.1

2.4%

reported any side effect — all mild

71.9%

used the kit at least once

96.4%

opened the kit they received

All outcomes were self-reported by verified purchasers. This is an observational study with no control group and no medical-record verification.

Exploratory cost analysis · illustrative only

One avoided visit can cost more than the whole kit.

The study modeled a perception-based, illustrative cost-offset scenario: among episodes where owners felt they avoided urgent care or the ER, the implied savings per episode ran from roughly $82 to $438, against a one-time kit price of $299.99.

One avoided visit can cost more than the whole kit.

$299.99

one-time kit price

Go deeper

Into The Wellness Company's findings

Owners reported strong engagement with the kit. They used it most often for respiratory illness, and nearly a third used it while traveling or in a remote setting. Among intended-use episodes, they reported rapid improvement, less disruption to daily life, and a high net benefit.

Respiratory illness led the way - 218 of 367 described episodes (59.4%).
Ready on the road - 31.1% used the kit while traveling or in a remote setting.
Fast relief, reported - 36.7% felt better within 24 hours; 81.6% within three days.
Value even unopened - most never-users still reported real peace-of-mind benefit.

Self-reported outcomes · intended-use episodes

95.8%Reported a positive benefitimproved within 3 days
Reported a net benefit (95.8%)
No positive difference reported
95.8%4.2%
Reduced need for urgent care / ER
Reduced disruption to daily life
Helped manage until care available
51.8%34.6%9.3%

Real-World Utilization, Outcomes, and Safety of Pre-Prescribed Emergency Medication Kits

Nicolas Hulscher, MPH; James A. Thorp, MD; Drew Pinsky, MD; Peter Gillooly, MSc; Foster Coulson; Melissa Annazone; Chloe Radesi; Jessica Brooks; Harvey Risch, MD, PhD; Peter A. McCullough, MD, MPH; Kelly Victory, MD. Affiliations: McCullough Foundation; The Wellness Company; Yale School of Public Health.

Published June 23, 2026 on Zenodo · DOI 10.5281/zenodo.20817624 •Read the full report →

What's inside

The Medical Emergency Kit

Eight prescription medications for adults 18+, prescribed after medical review by a licensed U.S. provider. Medications may be omitted based on your allergies and history.

Medication Strength / Quantity Class

Amoxicillin-Clavulanate

β-lactam antibiotic

875 mg · 28 tablets

β-lactam antibiotic

Azithromycin

Macrolide antibiotic

250 mg · 12 tablets

Macrolide antibiotic

Doxycycline

Tetracycline antibiotic

100 mg · 50 capsules

Tetracycline antibiotic

Trimethoprim-sulfamethoxazole

Sulfonamide antibiotic

800/160 mg · 28 tablets

Sulfonamide antibiotic

Metronidazole

Antibiotic / antiprotozoal

500 mg · 30 tablets

Antibiotic / antiprotozoal

Ivermectin

Antiparasitic

12 mg · 25 capsules

Antiparasitic

Fluconazole

Azole antifungal

150 mg · 2 tablets

Azole antifungal

Ondansetron

Antiemetic

4 mg tablets

Antiemetic

Printed guidebook

Clear directions and indications for every medication.

Telehealth consultation access

Talk to a licensed U.S. provider before you use it.

Replenishment for up to two years

Eligibility to refresh your kit as it's used or ages out.

Be ready before the next illness, trip, emergency, or access-to-care delay.

Prescribed by a licensed Wellness Company provider before kits are dispensed. Must be 18 years or older.

See the complete study

Read Now

Real-world use

Conditions treated in real-world use

Among owners who reported using their kit, respiratory illness was the most common reason — followed by urinary, gastrointestinal, dental, and skin or soft-tissue concerns, plus other acute conditions that come up when timely care is hard to reach.

Respiratory illness

59.4%

Urinary symptoms

15.0%

Other / not sure

7.4%

Gastrointestinal

6.3%

Dental concern

5.7%

Skin / soft tissue

4.1%

Preparedness starts before you need it.
Be ready

Preparedness starts before you need it.

When care is delayed, far away, or simply unavailable, physician-prescribed medications already in the home may help your household act sooner — with guidance.

Important Note

This page summarizes an observational report based on self-reported patient outcomes from a cross-sectional survey of verified purchasers of The Wellness Company Medical Emergency Kit. It is intended for educational purposes and should not be read as medical advice or a guarantee of results for any individual. All diagnoses, outcomes, and perceptions of avoided care were self-reported and unverified. No medical-record review, claims confirmation, or comparison group was available, meaning that perceived reductions in urgent care or emergency department use should not be interpreted as demonstrated clinical effectiveness.

The authors state that these findings are hypothesis-generating and that large prospective, randomized trials are warranted in willing populations at risk for common illnesses covered in the kits. The Wellness Company and The McCullough Foundation remain committed to investigating medicine's unanswered questions and advancing scientific knowledge.

Authors & Disclosures

Nicolas Hulscher, MPH; James A. Thorp, MD; Drew Pinsky, MD; Peter Gillooly, MSc; Foster Coulson; Melissa Annazone; Chloe Radesi; Jessica Brooks; Harvey Risch, MD, PhD; Peter A. McCullough, MD, MPH; Kelly Victory, MD. All authors are affiliated with and/or receive salary support from The Wellness Company (TWC), which operates the telemedicine platform through which the emergency medical kits evaluated in this analysis were prescribed and dispensed. No external funding was received for this project.

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